August 2018

Top 5 Best Ways To Unclog Your Drain

The 5 Best Ways To Unclog Your Drains On A Budget

kitchen sink clogged in Toronto

Drains clog, and it usually sucks when they do. There is never a good time to have your plumbing back up and cause a stink. Drains clog for many reasons, hair, foreign objects, grease, and natural causes like root systems. Yes, tree roots can grow into your pipes and cause them to clog up, especially if items are going down the drain and toilet that shouldn’t be. Most of the time drains can be unclogged with some elbow grease and a few household items. Other times you may need to call upon a local plumber to come and clean your pipes for you. If the clog is located deep enough in the pipeline then you may require an industrial snake to get deep enough to loosen up the debris and pull it out. There are great websites out there like Advanced Plumbing in Toronto that can be great resources for finding plumbing solutions, and finding plumbers if needed. If you don’t have a local plumber that you can call upon, then you can take these 5 simple tips for unclogging drains and do your best plumbers impression. Good luck!

 

  1. The Hanger

Depending on the depth of the clog, an old wire hanger stretched out should give you enough reach to get ahold of hair clogs and foreign debris that might be logged just out of reach of your fingers. A hanger can operate like a snake, once you run it down the pipe you can twist it so that it scrapes and collects the debris or objects that are causing the drain to clog. If you bend the end of the hanger like. Fish hook before feeding it down the drain pipe, you will increase your chances of catching something in there, especially hair. The hanger isn’t as effective in the toilet bowls as it is in sink and shower drains. I do remember a time though that I recovered a pair of eyeglasses from the toilet using a coat hanger.  

  1. Boiling Hot Water and Dish Soap

Boiling hot water is great for so many things and unclogging drains is one of them. You can try it first without dish soap, but I always just pour it in first and let it sit for a few minutes. Soap and hot water are great for loosening up grease and grime, it can also act as a lubricant and help lodged objects that are stuck slide through. I usually use something like Dawn dish soap, pour about a quarter to a half cup down the drain and let it seep into the nooks and crannies needed to get things to move. Next, take some boiling hot water and start slowly pouring it into the drain, add a little, wait a minute, add a little, wait, rinse and repeat. Again, this is not something that is going to be effective for unclogging the toilet, but is great for sink and shower drains.

  1. Drain Snake

This is more than just a household item, you are going to need to make a trip to the local Home Depot and drain snake operator in torontopurchase yourself one of these, and that is the only reason it is third to the first two. A drain snake has a much further reach than a hanger and is typically designed to twist and turn as it snakes through the pipe. Most snakes have a claw-like extension that claw and grab at hair and debris in the pipes as you fish them through. Some snakes are operated manually, while others are machine operated. I am a huge fan of snakes and have a few on hand at all times. Mine are all manually operated, one day I may upgrade to a motorized plumbing snake. Hopefully, I never clog a toilet so bad that I need a motorized snake to shake things up.

  1. Draino Max Gel

I’m a fan of all their products, I have unclogged some nasty backups in the shower before with Draino. This makes the list at 4 because it’s not a common household item, otherwise, it’s the first thing I reach for if I know the pipes are clogged from hair and debris. Draino Max Gel is not something you use if there is a foreign object lodged in the pipe, nor is it used much in toilets. Draino is great for kitchen sinks that have grease and debris clogging up the pipes, it’s also good for bathroom sinks, and the hair clogs that typically happen in them. Pouring a bottle of Draino down the pipe and letting it sit for 15 minutes is a great way to get an idea of what you are dealing with. Small time clogs that have hair or grease building up will almost always be resolved with some liquid Draino, if the bottle doesn’t clear the clog, time to get a snake or hire a plumber.

  1. Baking Soda and Salt

unclogging drain in torontoThese are ingredients most of us have in our homes, and while it would make sense to rank it above Draino because of availability, it just hasn’t been as effective for me with my clogs. This is an effective unclogging method for new clogs. Maybe you gave the dog a bath, or maybe someone in the house shaved in the sink, or maybe someone dumped some bacon grease down the kitchen sink and didn’t run hot water with it. There could be many reasons like these that a drain could clog, having an accessible resource like baking soda, salt, and hot water available to address these issues promptly is a great start and can also be used as a preventative measure. The concoction is also pretty harmless, so there isn’t concerns about skin contact.

What Are Fluorescent Dyes

What Are Fluorescent Dyes?

excitation moleculeWe had an interesting request to blog about the Fluorescent Dyes that are out on the market. Before we do that though, let’s get you up to speed on Fluorescent Dyes. One of our content writers studied chemistry in college and had this to say.

Most biological research laboratories depend on Fluorescent Dyes during standard tests that require the use of fluorescent molecules. The dyes are becoming more widely used as more people researching are finding just how versatile these fluorescent dyes can be in addition to their sensitivity levels and quantitative capabilities. These fluorescent probes have many uses in the lab, they can detect protein location and activation, and have the ability to identify complex protein formations, in addition to conformational changes and monitor advanced biological processes in vivo.

The real benefit of these fluorescent molecules (fluorophores/fluors) in the laboratory is that they have a unique reaction to light that passes through them when compared to other molecules. As the light passes through, it actually gets absorbed by an electron of a fluorescent particle. This then generates energy in the electron and propels it to an exited state. While this moment of excitation is happening, there is energy that begins to dissipate from a molecular collision and/or gets transferred to a proximal molecule, and the energy that remains then gets emitted as a photon which intern brings the electron back to a grounded state. Typically, the emitted photon will carry less energy, as a result it usually has a longer wavelength than the photon that experienced excitation, this allows the emitted fluorescence to be distinguished from the excitation light. The excitation produces an emission from the fluorophore that is cyclical, and until the the fluorophore is damaged beyond use, researchers can continue to excite the fluors until it reaches that stage. Because of this, the fluors can emit numerous photons repeatedly during this cycle of excitation, as a result the emissions and fluorescent molecules can continue to be used for a vast range of research.

Fluorophores can thus emit numerous photons through this cycle of excitation and emission and fluorescent molecules are therefore used for a broad range of research applications. You can learn in detail how fluorescent molecules work.

 

 

 

Fluorescent Dyes

diagram of Alexa Fluor 488

• Alexa Fluor 488 Dye

This dye is very bright, it is a fluorescent green dye that experiences excitation that is commonly suited to the 488 nm laser line. This dye is great for generating stable imaging and flow cytometry. It should also be noted that the Alexa Fluor 488 dye is pH-insensitive over a very wide molar range.

These probes that contain high fluorescence in addition to high photo stability are often times better for detecting a low-abundance of biological micro structures that illuminate with increased sensitivity. It’s common for Alexa Fluor 488 dye molecules to become attached to a protein molecule when exposed at high molar ratios without experiencing significant self-quenching. This can enable brighter conjugates, and and provide a more detailed detection.

• Cyanine Dyes

Cyanine dyes are specific molecules that contain a polymethine bridge between two unique nitrogen atoms that have a delocalized charge. As the result of this structure, cyanine dyes are known to have incredibly high extinction coefficients. There are different substituents that allow for the control of these properties, those most commonly being absorbance wavelength, photo stability, and fluoros.

• IR Fluors
“Bright, photostable and hydrophilic near-IR dye that is spectrally similar to Alexa Fluor® 750 and Cy7® Dye.

Bright and hydrophilic, far-red-fluorescent dye excited by the 633 nm or 647 nm laser lines.”

• MB Dyes

M.B. Dyes Chemical & Silk Ind. (Pvt.) Ltd. is a manufacturer of diversified auxiliary chemicals and dyes/pigments for Textile, Leather and Paint Industries. We also deal with many raw materiel used in these industries. We produced gamut of these chemicals for customer convenience to lessen their worries regarding raw material regular supply from a single source. Our manufacturing unit is located in Gadoon Amazai Industrial Estate Swabi NWFP and producing more than 110 products.

• Classic Fluorescent Dyes

What’s a fluorescent probe? It is a fluorophore that has been designed to localize in an isolated region of a biological specimen or to react to a specified stimulus. The Fluroprobes are fluorescent and give researchers the ability to identify specific components of complex bio-molecular structures that include living cells. The dyes have also been used regularly to modify things like amino acids, peptides, proteins, carbs, and other bio-molecules.

About Fluorophore
From Wiki: https://en.wikipedia.org/wiki/Fluorophore

“A fluorophore (or fluorochrome, similarly to a chromophore) is a fluorescent chemical compound that can re-emit light upon light excitation. Fluorophores typically contain several combined aromatic groups, or planar or cyclic molecules with several π bonds.

Fluorophores are sometimes used alone, as a tracer in fluids, as a dye for staining of certain structures, as a substrate of enzymes, or as a probe or indicator (when its fluorescence is affected by environmental aspects such as polarity or ions). More generally they are covalently bonded to a macromolecule, serving as a marker (or dye, or tag, or reporter) for affine or bioactive reagents (antibodies, peptides, nucleic acids). Fluorophores are notably used to stain tissues, cells, or materials in a variety of analytical methods, i.e., fluorescent imaging and spectroscopy.

Fluorescein, by its amine reactive isothiocyanate derivative FITC, has been one of the most popular fluorophores. From antibody labeling, the applications have spread to nucleic acids thanks to (FAM (Carboxyfluorescein), TET,…). Other historically common fluorophores are derivatives of rhodamine (TRITC), coumarin, and cyanine. Newer generations of fluorophores, many of which are proprietary, often perform better, being more photostable, brighter, and/or less pH-sensitive than traditional dyes with comparable excitation and emission.”

5 Best Places To Buy CBD Oils Online

Where To Buy CBD Oils Online – Our Top 5 Online Stores

Most CBD oils and products that are derived from the oils can be found online. The world of CBD oils has taken off and the internet wasn’t slow to adjust and monetize. CBD oil sites are showing up on every corner of the web, some are legitimate companies, making legitimate efforts to provide high-quality CBD oils as pure as possible. Others in the game could care less where the CBD oils are extracted from, or if they are truly organic or not, nor do they care about the amazing health benefits CBD’s provide to people suffering from inflammation, anxiety, arthritis, TMJ, and other chronic illnesses. I use CBD oils, and I must say that there is a sense of calm that comes over me when I ingest them. I prefer the soft gels over vaping or even the candy, but that’s just preference. The convenience of buying CBD online is obvious, the drawbacks, of course, is that there are world class jerks out there trying to snatch up your hard earned money and selling you low-quality CBD oils in return. The other perks when purchasing online is that you can go read product reviews, watch testimonials, and engage other users online to learn more about their experience. Facebook groups and CBD forums are a great way to go about this. Social media is a hot spot for information, if someone has purchased CBD oils online, chances are they have shared the experience on social. So dig around and see what you can find about the vendor before jumping in and making a purchase. Reaching out to a vendor and seeing how responsive they also speak volumes about the experience you can expect to have. Responsive vendors that answer questions in a timely manner should be considered trustworthy, if you reach out to a vendor and don’t hear back for a few days and the response doesn’t fully answer your question, you might want to think twice about buying from them. Know what it is you want before you buy, research the products, and gain an understanding about what you should expect the CBD oils to do for you. Any website out there that is making outlandish claims and promises of cures and miracles should be avoided. Whatever your reason for buying CBD oils, we hope that you find what you are looking for and it provides the relief you are in need of. On that note, these are our top 5 places to buy CBD oils online.

1. Medicinal Essentials

essential hemp oils

https://medicinalessentials.com/

Our experience with Medicinal Essentials was great. We reached out via email and the response time was almost immediate, and that email exchange eventually led to a phone call where the conversation turned into something far more informative than I would have expected from an online vendor. I ordered CBD Oils and some topical salve. My joints from years of grappling are inflamed and the topical salve was recommended to me. I used the product for a month and I was rather surprised by the results. My elbows, wrists, and knees felt relief. My wrists hurt most of the time and having a topical ointment I can rub on for temporary relief is a blessing. I do a lot of typing during the day, then grapple in the evenings and neither of those arts are good on my joints. This experience as a whole was the best one I have had yet, the customer service was phenomenal, and the products were everything they talked them up to be. This is now my go-to spot online for buying CBD and Hemp products.

2. Green Roads World

where to buy cod oils online

https://www.greenroadsworld.com/

Buying from Green Roads World was also a solid experience. They are much bigger than Medicinal Essentials, so I didn’t get that warm “mom and pop” feeling when I was having email correspondences with whomever I was dealing with. The product shipped in a timely manner arrived in nice packaging and appeared to be everything they were advertising online. The 1500 MG dose was enough to take the edge off and allowed me to get the shut-eye I was in need of. It’s nice being able to consume something like this, relax, and not be high. The other benefit is that there isn’t the groggy feeling in the morning like you might have from smoking some green leaf. I do like the way the products were displayed on the website, it was a clean interface, easy for me to navigate, and I liked the selection they had. As far as taste is concerned, the CBD Oils were comparable to those I got from Medicinal Essentials.

3. Try The CBD

online store for CBD products

https://www.trythecbd.com

These guys are located in Colorado, and these days I pretty much love that place. I have made trips there in recent months and have really enjoyed consuming legalized marijuana while there. The community in Boulder is solid, it has the best dispensary in Colorado there, and the breweries have some really good local brews on tap. When I found Try The CBD online I immediately liked the landing page. Pretty much everything seemed to be on the page in an ongoing scroll. I like scrolling down a single page, rather than bouncing from page to page searching for different products. The experience was pretty good, the shipping time took a little longer than the others at this point but it turned out to be worth it. The oils really tasted different, there was a unique flavor that my palette picked up on but I couldn’t identify it. The CBD oils worked as advertised, again, taking the edge off and providing me the sense of calm I prefer at the end of my work days. I also ordered the CBD Shatter which I had never had before and was impressed by the flavor of that. After reading the description I found out that there are added terpenes for added flavor that mimics the strain profile of popular marijuana plants. They titles their website Try The CBD, so I did and I was impressed.

4. Barlean’s

bar leans hemp and cbd oils

https://www.barleans.com

Barlean’s is located in the Pacific North West which made them cool long before I ordered from them. If you have never made that trip, go visit and enjoy the local scene. Marijuana is legal in Washington State, and it was called the Evergreen State long before marijuana was ever legalized. Barlean’s seems like a pretty cool place, they make all sorts of healthy oils and CBD Hemp oils just happen to be one of them. The website was a little slow, and I’m a pretty impatient guy, so the lag was enough to get me shuffling in my chair, then I took a rip off my CBD pen and all was good. Seriously, it’s like that. I had contact with Barlean’s and asked a few questions about their products, these people definitely knew what they were talking about and you could tell they were passionate about what they did. All the enthusiasm was expected though, they make oils for a living including fish oils, flax oils, coconut oils, and CBD hemp oils. It was no surprise to that I was greeted on the other end of that line by a well informed CBD enthusiast. The products shipped on time, and they arrived well packed and ready for consumption. The oils were good, I would buy again. The only thing that didn’t jump out at me was the flavor. That might have been because I had previously tried that terpene infused CBD shatter from Try The CBD and the flavor was amazing. The overall experience was solid though.

5. Bluebird Botanical

bluebird botanical CBD oils

https://bluebirdbotanicals.com

These guys are doing it, I have seen them grow from a small little operation to absolutely crushing it online. I really like the product, I think they truly care about where their product is sourced from and the quality of the CBD shows that. I used to order from these guys regularly a year back but ventured on to try some of these other vendors that have been making noise online. I would definitely buy again but didn’t make a purchase to review for this article. I’ll tell you that when I was buying from them, they were super responsive, CBD oils shipped quick, produced tasted great, and the people I felt with all seemed to be genuine and truly cared about the experience people were having online with their products. The website was really clean, easy to navigate, and loaded pretty quick. I see them around a lot now, not sure how they got so big so quick but they did it. I had to squeeze them into my top 5 list for a few reasons, most of which are listed above, but one vibe I really got from them is that they really cared, it wasn’t just about getting a sale, it was about helping people and that always counts for something in my book.